If using a sharp reamer, half the drilling RPM and double the drilling feed are good starting points, and usually work well. Other factors to consider also make a big difference in successful reaming though.
Is the reamer a bit dull and producing a torn finish? (replace it if possible). If it's all you got, try some practice holes until you get your best working process down.
Is it cutting a bit big? (Make sure you aren't trying to remove too much stock, that you don't have too much runout, and maybe try coolant instead of oil).
Is it cutting a bit small? (First, check your reamer condition, then if using coolant, try switching to oil. Too little stock or too low a feed can sometimes cause this also as the reamer will mostly rub instead of cut. You can make a reamer cut a tiny bit larger by slipping a steel shim in wrapped around the reamer that covers almost half the flutes' circumference).
(Now by "cutting big" or "cutting small" I am referring to size of hole vs. size of reamer. If the hole you're trying to ream is .250" and your reamer cuts a hole that's .252" and the reamer measures .252" you have a different problem - mainly lack of intelligence!)