In 1979, Winchester introduced the .375 Winchester as a modernized, high-performance version of the .38-55 Winchester, a black powder cartridge from the 1880’s. .375 Winchester was introduced in 1978 along with the Winchester Model 94 “Big Bore” lever action rifle. Marlin (model 375), Savage (model 99) and Ruger (model 3) also introduced rifles chambered for the .375 Winchester, but very slow sales led to the demise of commercially available cartridges. Winchester officially stopped chambering rifles in .375 Winchester in 1987 and by 2002, only the TC Contender was the only commercial rifle available in the cartridge.
Though very similar in appearance to the older .38-55, .375 Winchester operates at much higher pressures (50,000 cup)
The lack of bullet selection for the .375 Winchester made reloading difficult, since most bullets available in the .375 caliber were intended for much faster cartridges, like the .375 H&H Magnum, and will generally not expand at .375 Winchester velocities. The .375 Winchester performs best with lighter bullets at around 2200 fps.