I have a slightly different tip on drilling Ultem 1000. It is a plastic that puts the heat directly to the bit or tap, and the drills will actually come out smoking hot. If you don't want a dragged/smeared drilled hole, what works for me is low RPM's and very heavy feeds with only a few pecks. It's important to feed heavy to stay in front of the heat, and to be certain that the drill retacts a good amount so that no chip get's drag back into the hole....because that's the kiss of death.
So for example, with a F drill: I'd drill at 800 RPMs, feed 15-20 ipm and peck like 4 times to go an inch deep. I haven't yet noticed a problem with the holes closing up.
For tapping, it's messy but WD-40 is a good lube (though I worry about oil absorbsion). I don't have have flood coolant, but that should suffice (mist coolant hardly cuts it).
As the others mentioned, it's a hard plastic that chips real easy, especially where the tool exits a cut. So program accordingly and smartly, and add a typical bottom finish cut of .025-.040" to clean up chipped edges. Otherwise, it's a pretty easy to machine plastic that's pretty resistent to melting.
As for 2300-series. 30% glass, I'm not certain how much it's going to effect machining properties. But abrasion is definitely going to be an issue in a production scenerio, but it's not going to be on the order with like G10 or something. Let us know how it works out!