OK, you've got several things to think about:
1. How will the data from the presetter (typically gauge length and radius or diameter) be recorded, and how will it be fed into the controller of the machine? And how will it stay matched to the physical tool, so that the tool changer and the controller are in sync about what is where?
There are very elaborate schemes with rfid chips and integrated networks, or you can hang a string-tag from mcmaster onto the tool, or whatever. But you need a system and everybody needs to be consistent or when Jo sets tools and Pat loads them things may go wrong.
Seems to me that this part of the workflow would be the biggest problem for a shop with multiple users, multiple machines, and the users aren't ultra skilled (or even if they are if they don't all use the same procedure.)
2. "manual" presetters like my ebloni require a particular process to get consistent answers - cleaning dust off with silly-putty, picking the biggest flute for radius, etc. This is not difficult, but if you have multiple people getting them to do it the same way will require thought.
3. Do you use workpiece probes (renishaw omp-40 for example?) - you'll want the numbers from probing and the numbers from the pre-setter to agree - which can be tricky because probes move a little and can be hard to preset.
Likewise, if you are using on-machine tool probes for tool size verification, wear measurement, broken tool detection, you'll need to sync them up with the offline pre-setter.
If your tolerances are easy/loose, #2 and #3 shouldn't be too hard. If your tolerances are close/tight, it can be harder.
(My elboni and my blum laser always match to better than a thou, but getting them to match to 0.000'2 is more work....)