I made furniture whose end was just about as high as anyone's, and we used biscuits for alignment for edge gluing. But we didn't always use glue on them, because the biscuits will swell from the moisture in the glue, which is why they hold so well. But all that extra glue trapped in the pockets takes a long time to fully dry out, and when it finally does the biscuits and wood over them shrink back to their original thickness. If you haven't waited long enuf before flattening and finishing the surface, you will be able to see the slight depressions, especially with a high gloss finish.
Also, the thinking behind a "spring joint", or slightly hollow joint pulled in, is that it puts the ends of the glue joint in compression, and makes the joint less prone to opening up during the dry season when the ends of the boards dry out thru the end grain more quickly than the rest of the stock.
Lastly, and probably most important for you, is you'll need to make nicely fitted cauls for the "live" edges so they don't get destroyed by the clamps. 3-1/2" thick stock will require some serious clamping force to make a good joint. One way of doing this is to put packing tape over the edges, and then use Bondo on some wood sticks to conform to the edges. Works really well and is fast and cheap, altho stinky.