OT - opening up as best we can. AKA - is it still just the seasonal flu? #3 - Page 75
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  1. #1481
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    be a whole lot easier once hes evicted from the WH

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  3. #1482
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    Quote Originally Posted by iwananew10K View Post
    be a whole lot easier once hes evicted from the WH
    place your bet darlin.

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  5. #1483
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    Default Opening up - seriously in Spain

    All 5 big vaccine makers will be exponentially expanding their supply capacities for about 6 months.
    AstraZ (UK), Sputnik V (RU), Modena and Pfizer (US) and the china jab.
    Plus about 9-19-50 others.

    It is relatively easy and relatively cheap to produce massive amounts more of a chemical coctail and accessories that are tiny, light, and mostly non-harmful.

    This is Practical Machinist.
    We all know that making 1000 million glass ampules per year, vs say 20 million per year, will actually reduce the costs 2 orders of magnitude by 10% each, or about 25% total in qty 1000 million per year.
    That is 1 Billion units/yr for each of the 5 majors, so far, already approved and in use by 40.000+ people for each drug, give or take.

    And upgrading the current oldish production lines with convenient government money and tax write-offs will actually be quite a bit better in terms of cost/unit, profits, balance sheet, and cash flow and flexibility and everything going onward.

    Given money, that the drug companies do have, and can now spend tax-free and tax-positive, due to government edicts, all the drug companies can very easily scale up production 100-fold.
    The new "dense" flex production lines will cost a fraction of what the old ones did, and work very much more efficiently.
    Sure, it will take 4-6-9 months, at worst, but not more.
    Current stuff can start to produce gear, while the next production line is upgraded, and then ripple on down the plant.
    Repeat.
    Where cost is not the primary driver, extremely fast developments are easy to do.

    This does not mean the new drugs will be more expensive - because of more expensive machinery, production lines, and some expensive 100M blunders that are inevitable.
    On the contrary.
    The new drugs will be much cheaper, very much cheaper, because the production volume in units/cost of machinery will drop by about 100x.

    Making glass vials, needles, syringes, dispensers, and automating them is very well known technology.

    For the first-time-ever all the majors can go to the best automation tech available in the year 2020, immediately, across all plants and production lines, all underwritten by covid-need write-offs, without worrying about amortisations and tax audits.
    Or equipment costs, essentially paid for by the massive volumes produced, even if just once.

    1 billion jabs of covid-19 vaccine at just 1$/dose costs charged for production automation and stuff allows them to re-build anything and everything, everywhere in the world, in every plant and line.
    I am only talking about automatisation in the production lines, nothing to do with the drugs, value, IP, etc.

    1 billion/yr = 34 M/yr per plant in 30 plants.
    100.000 / day per plant, essentially.
    4500 / hour.

    This is a low number, easily achieved in the process industry, even if some very complex and or slow processes are involved, by running large numbers of parallel processes in those areas.
    This would be if the covid vaccine had some hard to do unique processes.

    So far, based on their costs and production schedules projected, none of the vaccines have any major hurdles, apart from one needing to be kept and likely processed at - 70 C - easily achieved on a modern automated production line.

  6. #1484
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    Quote Originally Posted by michiganbuck View Post
    I'm thinking done is likely done. Seems the chance of throwing the election is near over.
    ....
    Good point, on to the next big thing - exactly *how* much money should I donate to the democrats in the Georgia senate contests?

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  8. #1485
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    Quote Originally Posted by jim rozen View Post
    Good point, on to the next big thing - exactly *how* much money should I donate to the democrats in the Georgia senate contests?
    All the money!

  9. #1486
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  10. #1487
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    Default New vacciines production - Covid and others

    Essentially, the worlds governments are underwriting a massive conversion for drugs companies to go into a contract manufacturer situation for drugs and chemicals -- investment for free -- all paid for by the governments = citizens of those countries.

    The drugs companies get paid to make themselves into a company akin to flextronics in consumer hw, that makes 300 M iphones at a time in 2 months.
    Involving 65 machining operations per phone, to very high precision.
    For about 6$ each, each iPhone carcass costs about 11$ and 6$ goes to flextronics for work.

    This is good.
    All the big drugs companies get to make all these high-speed high-efficiency massive-volume production lines.
    For about 1$ per dose.
    So, next, they can make anything and everything in drugs at 1/10 of their current cost or less and 100x the volume and 1000x less latency.

    I suspect:
    One or more of the drugs companies have already seen this business model.
    One or more are already implementing this.
    They can become something akin to the fabs who make processors for amd, intel, and nvidia.

    The first few drugs companies can grab large numbers of customers for whom they will be manufacturing drugs, just like a contract manufacturer for iPhones or whatever.
    They can make them in vastly higher quantity, very quickly, at very low cost -- no small drug manufacturer or lab can compete.

    This can mean that in the future any drug can be made in massive scale with near-zero latency.
    And that small-quantity specialist treatments for rare diseases can be made for similar low costs approaching 1-2-5$ per unit.

    So a tiny lab or research outfit that solves a rare disease (50 people in the world) can get 100 vials for maybe 500-1000$ total, and get them made in less than 20 days.
    Because the contract manufacturer is not the research outfit anymore, and their business would not benefit even if they charged 50.000$ / shot, for 50.
    And none of the 50 sick could pay it.
    And the other big 5 will be happy to make stuff in small lots for future business and good relations and future R&D.

    This is just like AWS from amazon, rackspace, box, spacex (massive volume in rockets), amazon, aliexpress.
    The big drugs companies can potentially now build the massive hw and production lines and automation - while also selling retail and wholesale white brands to everyone else.

    --
    Or what do You think ?
    They build these ultra modern ultra fast flex production lines, that can spit out 1B doses per year.
    Paid for by us, the popula.

    And after covid, they stop using them ?


    --
    It is vastly cheaper for us the popula to pay the drug companies for the production lines.
    We lose about 10.000$/per person per year, to the covid stuff.
    Between economic losses, travel, extra gov. debt. etc, it´s probably nearer 20k life-time total value per user tvpu.

    That is economic losses, not debt, not money that was taken out of Your pocket.

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    Voting in leftist tyrants doesn't seem to help.
    Please all make sure you go bankrupt in the 2nd lockdown, if you don't we'll do it for you, its for your own good.


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    Quote Originally Posted by SND View Post
    Voting in leftist tyrants doesn't seem to help.
    Please all make sure you go bankrupt in the 2nd lockdown, if you don't we'll do it for you, its for your own good.

    Oh aren't we a little ray of sunshine today.

  13. #1490
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    Quote Originally Posted by SND View Post
    Voting in leftist tyrants doesn't seem to help.
    Please all make sure you go bankrupt in the 2nd lockdown, if you don't we'll do it for you, its for your own good.
    I have weathered numerous downturns in the economy, it was not luck, it was fiscal responsibility, and not being mortgaged to the hilt. The banksters that loaned all that money are doing quite well!

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    Quote Originally Posted by Demon73 View Post
    place your bet darlin.
    Oh, you can bet your sweet ass he is going out. Care to make any predictions? Give you one guess sweetpea.....

  16. #1492
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    Quote Originally Posted by iwananew10K View Post
    be a whole lot easier once hes evicted from the WH
    Not easier, .........just less painful to watch and hear than the present twat

    The whole world's got the Covid bill to pay and that is gunna take eons, ...........the UK chancellor (finance minister) is already making cuts, which surprise surprise will affect the poorer of our society.

    So all in all, after Covid, expect a big enema

  17. #1493
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    ALL THE MONEY!

    Well, the stimulus check probably helped Biden.

    In the meantime, I almost feel sorry for the folks taken in by the big orange grifter:

    Fred Eshelman Sues True the Vote | Law & Crime

    Sweet sweet republican tears, the best kind. Still, $2.5M? How gullible do you have to be?

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  19. #1494
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    Wotatwat, .........makes you wonder how these folk get so rich in the first place, (well it does me)

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    Quote Originally Posted by hanermo View Post
    Essentially, the worlds governments are underwriting a massive conversion for drugs companies to go into a contract manuf.........
    --
    Or what do You think ?
    They build these ultra modern ultra fast oses per year.
    Paid for by us, the popula.

    And after covid, they stop using them ?



    --
    It is vastly cheaper for us the popula to pay the drug companies for the production lines.
    We lose about 10.000$/per person per year, to the covid stuff.
    Between economic losses, travel, extra gov. debt. etc, it´s probably nearer 20k life-time total value per user tvpu.

    That is economic losses, not debt, not money that was taken out of Your pocket.
    What I think is hopefully that a country other than the United States manages any vaccine production. After the Boeing 737 MAX fiasco and now the way the recent election was conducted it might be better to find someplace where the oversight has integrity.

  22. #1496
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    Quote Originally Posted by standardparts View Post
    it might be better to find someplace where the oversight has integrity.
    Sad to say, but IMHO that's a tall order pretty much anywhere in the world.

  23. #1497
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    Quote Originally Posted by Trueturning View Post


    On yous guys.

    Good ones.

    Biden worshiper.

    Virtue signaling.

    Gus on crack.

    Carl Marx.
    sucks now you singling out people

  24. #1498
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  25. #1499
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    Quote Originally Posted by Demon73 View Post
    place your bet darlin.
    I'll put $5,000 on that one.

    You can't be serious. Conspiracy theory is one thing, but total denial of reality is too much.

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  27. #1500
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    little donnie finally got the desk size he deserved.
    Attached Thumbnails Attached Thumbnails trump-desk.jpg  

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