Which is why it would be really helpful if you posted PHOTOS of the machine especially photos of its manufacturer's plate - if any - giving the details of the machine model, serial number, variant etc etc. None of which you've provided.
Your question is akin to asking one like 'I have a Ford car. I want to change the engine. Has anyone done this before and if so, how?'
The devil is ALWAYS in the detail.
And, BTW, you came here for free help. If you don't want to give information in return for getting information, you're a taker, not a contributor. Go and pay someone if you don't want to contribute, this place works on people giving as well as asking.
FWIW I think you've no hope of finding a spindle that will swap over cleanly and cheaply. My Kearns O type HBM - a lot smaller than what you're talking about - has its spindle honed to fit its bushings. Swapping it over would require a complete teardown of the entire spindle frame assembly and replacement bushings, or honing out the existing ones, probably hard chroming the replacement spindle back to size or oversize to fit to honed bushings etc etc. It wouldn't be fast & it wouldn't be cheap.
I'm with JR. Rip out the power drawbar stuff and use a manual one. This is one hell of a lot simpler than swapping out a spindle with a 50 taper nose for one with a Morse taper nose so you can then use a MT5-50 taper adaptor which gets you back to using 50 taper tooling. Which you could do right now if you either fixed what's broken or replaced it all with a manual drawbar.
I'm done with this anyway, do what you like. I think you're one of those types that are too high maintenance to be worth the time.
PDW[
What's up with this guy^^^ if there is anyone on here that has ever replaced a spindle on a Lucas horizontal mill please contact me. NO drama please